NY,NY: SILICONE NIPPLE PROSTHESIS

"Pink Perfect" Nipple Prosthesis www.pink-perfect.com Our nipple prosthesis is intended for women who have undergone breast reconstruction with nipple removal. The nipples are handmade from platinum grade silicone and match perfectly with your breasts. The nipples are attached to the body by using a medical adhesive which is strong enough for any day to day activity and is waterproof! There are two types of nipples we provide:​ ready-made ($280)and custom-made.($375) Ready-Made Nipples We provide ready-made nipples in 3 styles. Each style can come in 8 different color variations of pink/browThe nipple prosthesis will be sent to you using a courier service along with a bottle of adhesive and usage instructions. The adhesive is strong enough to keep the prosthesis on the breast for several days and is fully waterproof! With the right care, the nipple prosthesis can last for years since the silicone is a very durable material (we use platinum grade silicone only).

SPIRONOLACTONE & EPLERENONE in PRIMARY ALDOSTERONISM (CONN SYNDROME)

Integr Blood Press Control. 2013 Oct 4;6:129-138. eCollection 2013. Mineralocorticoid receptor antagonists: emerging roles in cardiovascular medicine. AUSTRALIA: Melbourne. PROF J.W.FUNDER Spironolactone was first developed over 50 years ago as a potent mineralocorticoid receptor (MR) antagonist with undesirable side effects; it was followed a decade ago by eplerenone, which is less potent but much more MR-specific. From a marginal role as a potassium-sparing diuretic, spironolactone was shown to be an extraordinarily effective adjunctive agent in the treatment of progressive heart failure, as was eplerenone in subsequent heart failure trials. Neither acts as an aldosterone antagonist in the heart as the cardiac MR are occupied by cortisol, which becomes an aldosterone mimic in conditions of tissue damage. The accepted term "MR antagonist", (as opposed to "aldosterone antagonist" or, worse, "aldosterone blocker"), should be retained, despite the demonstration that they act not to deny agonist access but as inverse agonists. The prevalence of primary aldosteronism is now recognized as accounting for about 10% of hypertension, with recent evidence suggesting that this figure may be considerably higher: in over two thirds of cases of primary aldosteronism therapy including MR antagonists is standard of care. MR antagonists are safe and vasoprotective in uncomplicated essential hypertension, even in diabetics, and at low doses they also specifically lower blood pressure in patients with so-called resistant hypertension. Nowhere are more than 1% of patients with primary aldosteronism ever diagnosed and specifically treated. Given the higher risk profile in patients with primary aldosteronism than that of age, sex, and blood pressure matched essential hypertension, on public health grounds alone the guidelines for first-line treatment of all hypertension should mandate inclusion of a low-dose MR antagonist. KEYWORDS: eplerenone, inverse agonists, primary aldosteronism, public health, spironolactone PMID: 24133375 [PubMed - as supplied by publisher] PMCID: PMC3796852 Free PMC Article

UK CORK & LEATHER INSOLE

www.ggfootcare.co.uk Leather upper Cork Insole (CORK DIFFICULT TO FIND) These are chemical free vegetable tanned genuine leather upper insoles, with first class natural soft cork. combining these quality materials you get a comfortable, soft and breathable insole. Suitable for any type of footwear. .Genuine soft Leather upper .Natural soft cork backing for extra comfort Available in sizes: UK 3/4, 5/6, 7, 8/9 10/11, 12/13 Eur Sizes 36/37, 38/39, 40/41, 42/43, 44/45, 46/47, SOLD IN PAIRS Our Price: £4.00 (+ delivery)

USA CREUTZFELDT-JAKOB DISEASE

CREUTZFELDT-JAKOB DISEASE - USA (NORTH CAROLINA), POTENTIAL SURGICAL EXPOSURE ***************************************************************************** A ProMED-mail post ProMED-mail is a program of the International Society for Infectious Diseases Date: Tue 11 Feb 2014 Source: The Piedmont News Station [edited] Novant Health Forsyth Medical Center announced Monday [10 Feb 2014] they are reaching out to 18 neurosurgery patients exposed to Creutzfeldt-Jakob disease, a degenerative neurological disorder that is incurable and invariably fatal. "Today [11 Feb 2014], we are reaching out to 18 neurosurgery patients who were exposed to Creutzfeldt-Jakob disease over the last 3 weeks at Forsyth Medical Center," said Jeff Lindsay, President of Forsyth Medical Center. According to the National Institute of Neurological Disorders and Stroke, Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. CJD affects about one person in every one million people per year worldwide. "While the CDC categorizes such risks as very low, any risk of transmission is simply unacceptable," said Lindsay. "On behalf of the entire team, I apologize to the patients and their families for this anxiety. We are committed to providing support to patients and their families." CJD [variant CJC] has been closely associated with mad cow disease (bovine spongiform encephalopathy), however Dr. Jim Lederer said this particular strain is not associated with mad cow disease. "The patient had sporadic CJD. This is important to note, because it is often incorrectly associated with mad cow disease [variant CJD]. It is not," said Dr. Jim Lederer. "On 18 Jan 2014, an operation was performed on a patient with symptoms that could have been attributed to CJD. There were reasons to suspect this patient may have CJD. As such, extra precautions to clean equipment should have been taken, but [were] not," said Dr. Jim Lederer. Forsyth Medical said the exposure occurred through surgical instruments that were not properly sterilized. The surgical instruments used during the surgery were sterilized using standard hospital procedures, however they were not subjected to the enhanced sterilization procedures necessary on instruments used in confirmed or suspected cases of CJD. A patient who had entered Forsyth Medical Center last month [January 2014] for back surgery said a hospital staff member contacted her on Monday [10 Feb 2014] saying she is one of 18 patients who may have been exposed to the disease. A [staff member] says that it's not the hospital's fault, but they are taking full responsibility." Doctors say it is rare that the exposed patients will develop the disease, but if the disease surfaces in patients, it likely won't happen for 20 to 30 years. Novant Health says they will keep tabs on the health of the 18 patients, watching for any signs of the disease for the rest of their lives. According to the CDC, prions, the infectious agents of CJD, may not be inactivated by means of routine surgical instrument sterilization procedures. The World Health Organization and the US Centers for Disease Control and Prevention recommend that instruments used in confirmed or suspected CJD cases be immediately destroyed after use; short of destruction, it is recommended that heat and chemical decontamination be used in combination to process instruments that come in contact with high-infectivity tissues. According to the CDC, no cases of iatrogenic transmission of CJD have been reported since 1976, when current sterilization procedures were adopted. "We believe the chances of transmission to another person [are] very, very low," said Dr. Jim Lederer. The operation at Forsyth Medical was performed on a patient who was "suspected and later confirmed" to have sporadic CJD. In a news conference, Forsyth Medical officials said the disease has no cure and may not show up in exposed patients for decades. CJD usually appears later in life and runs a rapid course. Typically, onset of symptoms occurs about age 60, and about 90 percent of individuals die within one year. In the early stages of disease, people may have failing memory, behavioral changes, lack of coordination, and visual disturbances. As the illness progresses, mental deterioration becomes pronounced, and involuntary movements, blindness, weakness of extremities, and coma may occur. The Department of Health and Human Services issued [the following] statement on Monday [10 Feb 2014]: "DHHS officials are aware of the incident at Novant Health Forsyth Medical Center and have been in contact with the facility. Our primary concern is the health, safety, and welfare of patients, and we will continue to closely monitor the situation," said Kevin Howell, DHHS spokesperson.

UK ROYAL SOCIETY of MEDICINE FREE VIDEOS

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OLYMPICS: AERIALS should increase work for Ortho & Neurosurgeons.

Interesting to see whether aerials will increase incidence of spinal injuries.

Pharmacy counting tray & spatula: source of infection.

COMMENT: Patients advised to buy SEALED pill containers. Pharmacy(USA)/Chemist(UK) plastic pill trays and spatulae not sterilized. Gloves and disposables safer. Also diabetic individually wrapped blood strips should be supplied. Pathogens found in Hospital strip containers.(CAP)