At a Toronto International Endocine conference,Melbourne (Clayton) Prince Henry's Institute, Senior Fellow Prof. John FUNDER AO, MD,PhD, FRCP,FRACP pointed out that Dr. Michal LYTINSKI published in Polish before Dr.Jerome CONN.
Primary Aldosteronism is missed in most hypertensives.. 20% of the Canadian population are hypertensive( 6,800,000) 10% of hypertensives have Primary Aldosteronism (680,000). Mainly undiagnosed at present through "cost, ignorance & indifference". Less than 1% of those with Primary Aldosteronism are screened; especially indicated in Atrial fibrillation.
"Guidelines for Primary Hypertension need revision".
Low potassium is not the main sign. Resistant hypertension, weakness and nocturnal polyuria are clinical clues. Small adrenal tumours may be seen on CT scans.
A quick diagnostic test of eplerenone (INSPRA) or spironolactone (ALDACTONE) will immediately drop blood pressure in patients with Primary Aldosteronism. INSPRA does not cause gynaecomastia or erectile disfunction..
