Donor Screening
Initially the donors are selected by the Nordic Cryobank staff, based on a number of parameters:- Sperm Quality
- Age
- Personality
- Education
- 3-4 Generation Family Health History
Further screening includes blood and urine analysis:
- Chemistry Panel
- Complete Blood Count
- Urinalysis
- ABO-Rh Blood typing
- HIV
- HTLV I/II
- Hepatitis B Surface Antigen
- Hepatitis B Core Antibody
- Hepatitis C Viral Antibody
- Syphilis (RPR)
- CMV IgG/IgM
- Chlamydia
- Gonorrheae
The genetic testing we do includes the following:
- 3-4 generation family medical history, which is reviewed by a trained genetic specialist or a medical doctor (all donors)
- Cystic Fibrosis screening for 32-86 mutations in the Cystic Fibrosis gene (all Caucasian donors)
- Chromosome analysis (all donors)
- Thalassemia (all donors). An HPLC analysis is done to detect this indirectly. Please contact us if you would like to have your donor genetically screened for carrier status. Less than 1 in 1000 are carriers for this disease in Northern Europe.
- Tay-Sachs disease (donors with Ashkenazi Jewish or French Canadian ancestry)
- Canavan disease disease (donors with Ashkenazi Jewish ancestry)
- Familial Dysautonomia (donors with Ashkenazi Jewish ancestry)
- Fanconi Anemia type C (donors with Ashkenazi Jewish ancestry)
- Gaucher disease (donors with Ashkenazi Jewish ancestry)
- Niemann-Pick type A disease (donors with Ashkenazi Jewish ancestry)
- Sickle Cell Disease (donors with African ancestry are genetically screened). For all donors an HPLC analysis is done to detect this indirectly.
- Canavan disease (donors with Ashkenazi Jewish ancestry)
It is impossible to rule out genetic disease with 100% certainty since it is not possible to test for all inheritable diseases.
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